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1

Role of “non-cardiac” voltage-gated sodium channels in cardiac cells

Jean-Sébastien Rougier, Hugues Abriel

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 141 KB

english, 2012

2

Inherited progressive cardiac conduction disorders

Baruteau, Alban-Elouen, Probst, Vincent, Abriel, Hugues

Journal:

Current Opinion in Cardiology

Year:

2015

Language:

english

File:

PDF, 225 KB

english, 2015

3

Lateral Membrane-Specific MAGUK CASK Down-Regulates Na V 1.5 Channel in Cardiac Myocytes

Eichel, Catherine A, Beuriot, Adeline, Chevalier, Morgan, Rougier, Jean-Sébastien, Louault, Florent, Dilanian, Gilles, Amour, Julien, Coulombe, Alain, Abriel, Hugues, Hatem, Stephane N, Balse, Elise

Journal:

Circulation Research

Year:

2016

Language:

english

File:

PDF, 2.99 MB

english, 2016

4

Refining the molecular organization of the cardiac intercalated disc

Vermij, Sarah H., Abriel, Hugues, van Veen, Toon A. B.

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

5

Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization

Liliana Sintra Grilo, Pierre-Alain Carrupt, Hugues Abriel, Antoine Daina

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

6

Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination

Staub, Olivier, Abriel, Hugues, Plant, Pamela, Ishikawa, Toru, Kanelis, Voula, Saleki, Reza, Horisberger, Jean-Daniel, Schild, Laurent, Rotin, Daniela

Journal:

Kidney International

Year:

2000

Language:

english

File:

PDF, 471 KB

english, 2000

7

Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes

Jean-Sébastien Rougier, Olivier Muller, Stefan Berger, Gabriel Centeno, Günther Schütz, Dmitri Firsov, Hugues Abriel

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 256 KB

english, 2008

8

Feedback inhibition of rat amiloride-sensitive epithelial sodium channels expressed in Xenopus laevis oocytes

Hugues Abriel, Jean-Daniel Horisberger

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 1.99 MB

english, 1999

9

Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors

DARKO KRANJČEC, MIJO BERGOVEC, JEAN-SÉBASTIEN ROUGIER, MIROSLAV RAGUZ, SONJA PAVLOVIC, THOMAS JESPERSEN, VINCENT CASTELLA, DAGMAR I. KELLER, HUGUES ABRIEL

Journal:

Pacing and Clinical Electrophysiology

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

10

Patient with Syncope and LQTS Carrying a Mutation in the PAS Domain of the hERG1 Channel

Liliana Sintra Grilo, Jürg Schläpfer, Florence Fellmann, Hugues Abriel

Journal:

Annals of Noninvasive Electrocardiology

Year:

2011

Language:

english

File:

PDF, 302 KB

english, 2011

11

Male and female equality: still far from goal

Liliana Sintra Grilo, Hugues Abriel

Journal:

The Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

12

Regulation of the Voltage-Gated Cardiac Sodium Channel Nav1.5 by Interacting Proteins

Hugues Abriel, Robert S. Kass

Journal:

Trends in Cardiovascular Medicine

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

13

Cardiac sodium channel Nav1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

Thomas Jespersen, Bruno Gavillet, Miguel X. van Bemmelen, Sophie Cordonier, Marc A. Thomas, Olivier Staub, Hugues Abriel

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 383 KB

english, 2006

14

Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation

Andrea A. Domenighetti, Christophe Boixel, Daniel Cefai, Hugues Abriel, Thierry Pedrazzini

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 303 KB

english, 2007

15

Crosstalk between cardiac ion channel subunits: An encrypted language to be deciphered

Séverine Petitprez, Hugues Abriel

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 253 KB

english, 2008

16

Cardiac sodium channel Nav1.5 and interacting proteins: Physiology and pathophysiology

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

17

Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1

Maxime Albesa, Liliana Sintra Grilo, Bruno Gavillet, Hugues Abriel

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

18

Role of the intracellular domain of the β subunit in Na,K pump function

Hugues Abriel, Udo Hasler, Käthi Geering, Jean-Daniel Horisberger

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

19

Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4

Hugues Abriel, Elena Kamynina, Jean-Daniel Horisberger, Olivier Staub

Journal:

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

20

Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

Jacob Tfelt-Hansen, Thomas Jespersen, Jacob Hofman-Bang, Hanne Borger Rasmussen, Pernille Cedergreen, Flemming Skovby, Hugues Abriel, Jesper Hastrup Svendsen, Soren-Peter Olesen, Michael Christiansen,

Journal:

Canadian Journal of Cardiology

Year:

2009

File:

PDF, 1008 KB

2009

21

TRPM4 channels in the cardiovascular system: Physiology, pathophysiology, and pharmacology

Hugues Abriel, Ninda Syam, Valentin Sottas, Mohamed Yassine Amarouch, Jean-Sébastien Rougier

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

22

Cardiac channelopathies: Genetic and molecular mechanisms

Abriel, Hugues, Zaklyazminskaya, Elena V.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

23

Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: The multiple pool model

Shy, Diana, Gillet, Ludovic, Abriel, Hugues

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 600 KB

english, 2013

24

Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells

Amarouch, Mohamed-Yassine, Syam, Ninda, Abriel, Hugues

Journal:

Neuroscience Letters

Year:

2013

Language:

english

File:

PDF, 588 KB

english, 2013

25

Na V 1.5 and interacting proteins in human arrhythmogenic cardiomyopathy

Gillet, Ludovic, Shy, Diana, Abriel, Hugues

Journal:

Future Cardiology

Year:

2013

Language:

english

File:

PDF, 315 KB

english, 2013

26

The Anchoring Protein SAP97 Is Crucial For The Surface Expression Of Shal Kv Potassium Channels And Their Regulation By CaMKII In Cardiac Myocytes

El-Haou, Saïd, Balse, Elise, Neyroud, Nathalie, Gavillet, Bruno, Abriel, Hugues, Coulombe, Alain, Jeromin, Andreas, Hatem, Stephane N.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

27

Regulation of the Cardiac Iks Channel Complex by Ubiquitylation and De-Ubiquitylation

Krzystanek, Katarzyna, Grunnet, Morten, Olesen, Søren Peter, Abriel, Hugues, Jespersen, Thomas

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

28

Fluidfm for Force Controlled Electrophysiology

Ossola, Dario, Behr, Pascal, Amarouch, Mohamed-Yassine, Abriel, Hugues, Vörös, Janos, Zambelli, Tomaso

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

29

Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes

Clémençon, Benjamin, Fine, Michael, Lüscher, Benjamin, Baumann, Marc U., Surbek, Daniel V., Abriel, Hugues, Hediger, Matthias A.

Journal:

Protein Expression and Purification

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

30

Deubiquitylating enzyme USP2 counteracts Nedd4-2–mediated downregulation of KCNQ1 potassium channels

Krzystanek, Katarzyna, Rasmussen, Hanne Borger, Grunnet, Morten, Staub, Olivier, Olesen, Søren-Peter, Abriel, Hugues, Jespersen, Thomas

Journal:

Year:

2012

Language:

english

File:

PDF, 2.37 MB

english, 2012

31

TRPM4 Genetic Variants in Patients with Congenital Atrio-Ventricular Block

Syam, Ninda, Chatel, Stephanie, Rougier, Jean-Sebastien, Sottas, Valentin, Baruteau, Alban, Probst, Vincent, Schott, Jean-Jacques, Abriel, Hugues

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 50 KB

english, 2014

32

Glycosylation of TRPM4 and TRPM5 Channels: Molecular Determinants and Functional Aspects

Syam, Ninda R.M., Rougier, Jean-Sebastien, Abriel, Hugues

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

33

Takotsubo cardiomyopathy and congenital long QT syndrome in a patient with a novel duplication in the Per-Arnt-Sim (PAS) domain of hERG1

Grilo, Liliana Sintra, Pruvot, Etienne, Grobéty, Michel, Castella, Vincent, Fellmann, Florence, Abriel, Hugues

Journal:

Year:

2010

Language:

english

File:

PDF, 2.76 MB

english, 2010

34

Regulation of the Cardiac Sodium Channel Nav1.5 by Utrophin in Dystrophin Deficient Mice

Abriel, Hugues, Albesa, Maxime, Ogrodnik, Jakob, Rougier, Jean-Sébastien

Journal:

Year:

2010

Language:

english

File:

PDF, 186 KB

english, 2010

35

0265: A novel SCN5A mutation associated with exercise-induced polymorphic ventricular arrhythmias resembling CPVT

Amarouch, Mohamed Yassine, Leinonen, Jaakko, Marjamaa, Annukka, Kucera, Jan P., Laitinen-Forsblom, Päivi J., Lahtinen, Annukka M., Palotie, Aarno, Kontula, Kimmo, Toivonen, Lauri, Abriel, Hugues, Wide

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2014

Language:

english

File:

PDF, 51 KB

english, 2014

36

0150: PDZ domain proteins interacting with Nav1.5 differentially regulate Nav1.5 channel pools in mouse cardiomyocytes

Gillet, Ludovic, Shy, Diana, Sonntag, Stephan, Rougier, Jean-Sébastien, Verkerk, Arie, Essers, Maria, Marsman, Roos, Shmerling, Doron, Bezzina, Connie, Remme, Carol Ann, Abriel, Hugues

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

37

Characterization of 2 Genetic Variants of Na v 1.5-Arginine 689 Found in Patients with Cardiac Arrhythmias

SOTTAS, VALENTIN, ROUGIER, JEAN-SÉBASTIEN, JOUSSET, FLORIAN, KUCERA, JAN P., SHESTAK, ANNA, MAKAROV, LEONID M., ZAKLYAZMINSKAYA, ELENA V., ABRIEL, HUGUES

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2013

Language:

english

File:

PDF, 983 KB

english, 2013

38

Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients

Fodstad, Heidi, Bendahhou, Saïd, Rougier, Jean‐Sébastien, Laitinen‐Forsblom, Päivi J., Barhanin, Jacques, Abriel, Hugues, Schild, Laurent, Kontula, Kimmo, Swan, Heikki

Journal:

Annals of Medicine

Year:

2006

Language:

english

File:

PDF, 456 KB

english, 2006

39

Cardiac Sodium Channel Disorders: One Gene with Many Genetic Variants Leading to Many Cardiac Phenotypes

Journal:

Cardiac Electrophysiology Clinics

Year:

2014

Language:

english

File:

PDF, 153 KB

english, 2014

40

Cardiac Sodium Channel Nav1.5 and Drug-Induced Long QT Syndrome

Journal:

Cardiac Electrophysiology Clinics

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

41

β-Blockers in Congenital Short-QT Syndrome as Ion Channel Blockers

ABRIEL, HUGUES, ROUGIER, JEAN-SÉBASTIEN

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

42

Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current

Gillet, Ludovic, Rougier, Jean-Sébastien, Shy, Diana, Sonntag, Stephan, Mougenot, Nathalie, Essers, Maria, Shmerling, Doron, Balse, Elise, Hatem, Stéphane N., Abriel, Hugues

Journal:

Year:

2015

Language:

english

File:

PDF, 2.25 MB

english, 2015

43

Force-Controlled Patch Clamp of Beating Cardiac Cells

Ossola, Dario, Amarouch, Mohamed-Yassine, Behr, Pascal, Vörös, János, Abriel, Hugues, Zambelli, Tomaso

Journal:

Year:

2015

Language:

english

File:

PDF, 5.20 MB

english, 2015

44

Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications

Marionneau, Céline, Abriel, Hugues

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

45

Na + channel function, regulation, structure, trafficking and sequestration

Chen-Izu, Ye, Shaw, Robin M., Pitt, Geoffrey S., Yarov-Yarovoy, Vladimir, Sack, Jon T., Abriel, Hugues, Aldrich, Richard W., Belardinelli, Luiz, Cannell, Mark B., Catterall, William A., Chazin, Walter

Journal:

The Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 494 KB

english, 2015

46

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels

Rougier, Jean-Sebastien, Albesa, Maxime, Syam, Ninda, Halet, Guillaume, Abriel, Hugues, Viard, Patricia

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 1015 KB

english, 2015

47

Cardiac Electrophysiology: From Cell to Bedside || Contributors

Year:

2014

Language:

english

File:

PDF, 347 KB

english, 2014

48

Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx5cv mice

Rougier, Jean-Sébastien, Gavillet, Bruno, Abriel, Hugues

Journal:

Frontiers in Physiology

Year:

2013

Language:

english

File:

PDF, 433 KB

english, 2013

49

Computational tools to investigate genetic cardiac channelopathies

Abriel, Hugues, de Lange, Enno, Kucera, Jan P., Loussouarn, Gildas, Tarek, Mounir

Journal:

Frontiers in Physiology

Year:

2013

Language:

english

File:

PDF, 323 KB

english, 2013

50

Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels

Amarouch, Mohamed-Yassine, Abriel, Hugues

Journal:

Frontiers in Physiology

Year:

2015

Language:

english

File:

PDF, 2.52 MB

english, 2015